Details for gene set NCI_SPHINGOSINE 1-PHOSPHATE (S1P) PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB
Phenotype	phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB
Upregulated in class	WTpreB
GeneSet	NCI_SPHINGOSINE 1-PHOSPHATE (S1P) PATHWAY
Enrichment Score (ES)	-0.6666101
Normalized Enrichment Score (NES)	-1.7094414
Nominal p-value	0.0
FDR q-value	0.010424511
FWER p-Value	0.089

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	BAX	17832	644	4.463	-0.0074	No
2	CYCS	8821	744	4.120	0.0125	No
3	CTSD	22	994	3.332	0.0194	No
4	MAPK8	6459	1644	2.061	-0.0030	No
5	BID	17017 435	1954	1.590	-0.0100	No
6	BAG4	7431	2121	1.411	-0.0103	No
7	BCAR1	18741	2225	1.277	-0.0080	No
8	PRKCZ	5260	2281	1.203	-0.0036	No
9	PAWR	19885 658	2446	1.028	-0.0062	No
10	HRAS	4868	2610	0.906	-0.0094	No
11	SLC9A3R2	23089 1544 1514	3024	0.543	-0.0284	No
12	ITGB3	20631	3043	0.531	-0.0262	No
13	VEGFA	22969	3350	0.369	-0.0404	No
14	FADD	17536 8950 4711	3666	0.282	-0.0557	No
15	GNAI1	9024	3780	0.255	-0.0603	No
16	SHC1	9813 9812 5430	3936	0.225	-0.0673	No
17	GNAQ	4786 23909 3685	4136	0.194	-0.0769	No
18	AKT1	8568	4218	0.183	-0.0801	No
19	GNAZ	71	4228	0.182	-0.0795	No
20	BCL2	8651 3928 13864 4435 981 4062 13863 4027	4380	0.162	-0.0867	No
21	FYN	3375 3395 20052	5072	0.109	-0.1233	No
22	SNX15	23993 3761	5222	0.100	-0.1308	No
23	SPHK1	5484 1266 1402	5473	0.088	-0.1438	No
24	SRC	5507	5727	0.076	-0.1570	No
25	IGF1	3352 9156 3409	6411	0.055	-0.1936	No
26	GNAO1	4785 3829	6926	0.044	-0.2211	No
27	PTGS2	5317 9655	7102	0.040	-0.2303	No
28	STAT5B	20222	7325	0.036	-0.2421	No
29	PAK1	9527	7590	0.031	-0.2562	No
30	SHB	10493	7714	0.029	-0.2626	No
31	HIF1A	4850	7746	0.029	-0.2641	No
32	NCK1	9447 5152	7819	0.028	-0.2679	No
33	KDR	16509	8027	0.024	-0.2789	No
34	GRB10	4799	8036	0.024	-0.2792	No
35	PDGFB	22199 2311	8207	0.022	-0.2882	No
36	GNA14	23907	8214	0.022	-0.2884	No
37	RHOA	8624 4409 4410	8261	0.021	-0.2908	No
38	PTPN2	23414	8306	0.020	-0.2930	No
39	GNA12	9023	8597	0.016	-0.3086	No
40	ACP1	4317	9230	0.009	-0.3427	No
41	PTPN11	5326 16391 9660	9360	0.007	-0.3497	No
42	FLT1	3483 16287	9989	-0.001	-0.3836	No
43	IRS1	4925	10290	-0.005	-0.3998	No
44	CDC42	4503 8722 4504 2465	10407	-0.006	-0.4060	No
45	LYN	16281	10463	-0.007	-0.4090	No
46	CRADD	19640	10936	-0.013	-0.4344	No
47	YES1	5930	10960	-0.014	-0.4356	No
48	LRP1	9284	11848	-0.027	-0.4833	No
49	PLCB2	5262	11963	-0.029	-0.4893	No
50	DOK1	17104 1018 1177	12045	-0.031	-0.4935	No
51	EGF	15169	12130	-0.033	-0.4978	No
52	PIK3R1	3170	12502	-0.041	-0.5177	No
53	PLCG1	14753	12675	-0.046	-0.5267	No
54	SOS1	5476	13046	-0.056	-0.5463	No
55	GNAI3	15198	13219	-0.062	-0.5552	No
56	SPHK2	1217 1806 12155	13302	-0.065	-0.5593	No
57	PDGFRB	23539	13453	-0.070	-0.5670	No
58	PIK3CA	9562	13540	-0.075	-0.5711	No
59	ASAH1	3835 3853 8630	13543	-0.075	-0.5708	No
60	TNF	23004	13668	-0.082	-0.5770	No
61	ABL1	2693 4301 2794	14050	-0.106	-0.5969	No
62	GRB7	20673	14124	-0.112	-0.6002	No
63	PDGFA	5237	14395	-0.140	-0.6139	No
64	CBL	19154	14602	-0.166	-0.6241	No
65	FOS	21202	14800	-0.201	-0.6335	No
66	SMPD3	18757	14820	-0.203	-0.6333	No
67	MAP2K2	19933	14908	-0.221	-0.6366	No
68	GNA15	19671	14942	-0.226	-0.6370	No
69	VAV2	5848 2670	14978	-0.236	-0.6375	No
70	JAK2	23893 9197 3706	15111	-0.267	-0.6430	No
71	STAT5A	20664	15113	-0.268	-0.6414	No
72	AIFM1	2558 24161	15116	-0.268	-0.6398	No
73	MAP2K1	19082	15318	-0.325	-0.6487	No
74	MYC	22465 9435	15334	-0.330	-0.6475	No
75	LCK	15746	15440	-0.368	-0.6509	No
76	TNFRSF1A	1181 10206	15447	-0.370	-0.6490	No
77	CDH5	18512	15470	-0.378	-0.6478	No
78	FGR	4723	15758	-0.526	-0.6601	No
79	MAP4K4	11241	15849	-0.588	-0.6614	No
80	ITGAV	4931	15941	-0.673	-0.6622	Yes
81	HCK	14787	15979	-0.695	-0.6599	Yes
82	RIPK1	5381	16037	-0.757	-0.6584	Yes
83	PTPN1	5325	16168	-0.897	-0.6599	Yes
84	TRAF2	14657	16252	-0.981	-0.6584	Yes
85	PTPRJ	9664	16387	-1.089	-0.6589	Yes
86	NCK2	9448	16530	-1.250	-0.6589	Yes
87	RAC1	16302	16651	-1.434	-0.6566	Yes
88	BIRC3	19247	16725	-1.544	-0.6511	Yes
89	AKT3	13739 982	16769	-1.612	-0.6436	Yes
90	RASA1	10174	16815	-1.689	-0.6356	Yes
91	MAPK3	6458 11170	16931	-1.809	-0.6308	Yes
92	SMPD1	18145 2658	16969	-1.861	-0.6213	Yes
93	CASP8	8694	17013	-1.927	-0.6119	Yes
94	MAP2K4	20405	17051	-1.981	-0.6017	Yes
95	RAF1	17035	17131	-2.125	-0.5929	Yes
96	SGPL1	19757	17239	-2.305	-0.5846	Yes
97	PRKCD	21897	17290	-2.395	-0.5726	Yes
98	MAPK14	23313	17421	-2.682	-0.5632	Yes
99	BAD	24000	17524	-2.914	-0.5508	Yes
100	SGPP1	21039	17527	-2.920	-0.5330	Yes
101	GRB2	20149	17590	-3.055	-0.5177	Yes
102	PRKRA	357	17594	-3.069	-0.4990	Yes
103	JUN	15832	17687	-3.335	-0.4835	Yes
104	GNA13	20617	17715	-3.402	-0.4641	Yes
105	SLC9A3R1	11250	17768	-3.541	-0.4452	Yes
106	NFKB1	15160	17789	-3.591	-0.4243	Yes
107	GNA11	3300 3345 19670	17835	-3.697	-0.4041	Yes
108	NFKBIA	21065	17838	-3.699	-0.3815	Yes
109	RELA	23783	17959	-4.092	-0.3629	Yes
110	PTEN	5305	18200	-4.996	-0.3452	Yes
111	GAB1	18828	18283	-5.430	-0.3164	Yes
112	STAT1	3936 5524	18294	-5.505	-0.2832	Yes
113	CSK	8805	18359	-5.871	-0.2506	Yes
114	BLK	3205 21791	18378	-5.983	-0.2149	Yes
115	MAP3K1	21348	18411	-6.282	-0.1781	Yes
116	STAT3	5525 9906	18455	-6.760	-0.1390	Yes
117	DNM2	4635 3103	18471	-6.991	-0.0969	Yes
118	CXCR4	13844	18551	-7.968	-0.0524	Yes
119	MAPK1	1642 11167	18592	-9.104	0.0013	Yes